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Fọ́sókínásì (PKase)
Nípa Phosphokinase
ES-PKase (Phosphokinase): n ṣe iranlọwọ fun gbigbe awọn ẹgbẹ fosfeti lori ATP si awọn agbo-ogun miiran. O tun n ṣe iranlọwọ fun gbigbe awọn ẹgbẹ fosfeti lori awọn nucleosides miiran ti triphosphate nigba miiran. Pupọ julọ awọn kinases nilo awọn ion irin divalent lati kopa ninu iṣe (ni gbogbogbo Mg2+). Iru awọn ọja enzyme PKase 21 lo wa (Nọmba bi ES-PKase101~ ES-PKase-121) ti SyncoZymes ṣe agbekalẹ rẹ.
Irú ìṣesí àbájáde:
Foonu alagbeka/Wechat/WhatsApp: +86-13681683526
Imeeli:lchen@syncozymes.com
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Cyclooxygenase (COX)
Nípa Cyclooxygenase
ES-COX (Cyclooxygenase): ń ṣe àtúnṣe ìyípadà àwọn ìsopọ̀ C=C sí epoxide. Irú àwọn ọjà enzyme COX 11 ló wà (Nọ́mbà gẹ́gẹ́ bí ES-COX101~ ES-COX-111) tí SyncoZymes ṣe. Gẹ́gẹ́ bí onírúurú ìlànà catalytic, a pín COX ti SyncoZymes sí haloperoxidase àti styrene monooxygenase. ES-COX101, 102, 107-111 jẹ́ ti haloperoxidase, nígbà tí ES-COX103-106 jẹ́ ti styrene monooxygenase.
Foonu alagbeka/Wechat/WhatsApp: +86-13681683526
Imeeli:lchen@syncozymes.com
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Cyclohexanone monooxygenase (CHMO)
Nípa Cyclohexanone monooxygenase
ES-CHMO (Cyclohexanone monooxygenase): Baeyer Villiger monooxygenase (BVMO) kan pẹlu cyclohexanone gẹgẹbi ipilẹ, le ṣe oxidize cyclohexanone si cyclohexanol nipa lilo oxygen.
Ó jẹ́ irú enzyme tí ó gbára lé flavin. Flavin tí a ti sọ di oxidized ni a dínkù sí flavin nípasẹ̀ ìyípo tí ó ń dín coenzyme II (NADPH) kù fún ìyípo tí ó tẹ̀lé e. Nítorí náà, cofactor NADPH ṣe pàtàkì nínú ìyípo flavin. Irú enzyme CHMO kan ṣoṣo ló wà (Nọ́mbà gẹ́gẹ́ bí ES-CHMO101) tí SyncoZymes ṣe, èyí tí a lè lò láti ṣe ìyípo cyclohexanone sí cyclohexanone.
Irú ìṣesí àbájáde:
Foonu alagbeka/Wechat/WhatsApp: +86-13681683526
Imeeli:lchen@syncozymes.com
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Carboxylic acid reductase (CAR)
Nípa Carboxylic acid reductase
ES-CAR (Carboxylic acid reductase): ń ṣe àtúnṣe ìdínkù ẹgbẹ́ carboxyl sí ẹgbẹ́ aldehyde. Nínú ìlànà catalytic, a nílò ìṣiṣẹ́ ATP àti coenzyme NADPH gẹ́gẹ́ bí àwọn olùgbé hydrogen. Irú àwọn ọjà enzyme CAR méjì ló wà (Nọ́mbà bíi ES-CAR101~ ES-CAR-102) tí SyncoZymes ṣe.
Irú ìṣesí àbájáde:
Foonu alagbeka/Wechat/WhatsApp: +86-13681683526
Imeeli:lchen@syncozymes.com
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Eluxadoline Agbedemeji methyl 5-(((S)-2-((tert-butoxycarbonyl)amino)-3-(4-carbamoyl-2,6-dimethylphenyl)-N-((S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl)propanamido)methyl)-2-methoxybenzoate
Àkójọ ìwé nọ́mbà SZ-2078
CAS: 1137026-67-5
Ìmọ́tótó: 99%
Lilo Eluxadoline
Foonu alagbeka/Wechat/WhatsApp: +86-13681683526
Imeeli:lchen@syncozymes.com
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Eluxadoline Intermediate (S)-Methyl 2-Methoxy-5-((1-(4-phenyl-1H-imidazol-2-yl)ethylamino)methyl)benzoate
Àkójọ ìwé nọ́mbà SZ-2077
CAS: 1391712-57-4
Ìmọ́tótó: 99%
Lilo Eluxadoline
Foonu alagbeka/Wechat/WhatsApp: +86-13681683526
Imeeli:lchen@syncozymes.com
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Adapalene Intermediate 1-(5-bromo-2-methoxy-phenyl)adamantane
Àkójọ ìwé nọ́mbà SZ-1559
CAS: 104224-63-7
Ìmọ́tótó: 99%
Lilo Adpalene
Foonu alagbeka/Wechat/WhatsApp: +86-13681683526
Imeeli:lchen@syncozymes.com
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Eluxadoline Intermediate (S)-Methyl 2-Methoxy-5-((1-(4-phenyl-1H-imidazol-2-yl)ethylamino)methyl)benzoate oxalic acid
Àkójọ ìwé nọ́mbà SZ-2077
CAS: 2046303-09-5
Ìmọ́tótó: 99%
Lilo Eluxadoline
Foonu alagbeka/Wechat/WhatsApp: +86-13681683526
Imeeli:lchen@syncozymes.com
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Ibrutinib Intermediate (S)-1-Boc-3-hydroxypiperidine
Àkójọ ìwé nọ́mbà SZ-1527
CAS: 143900-44-1
Ìmọ́tótó: 99%
Lilo Ibrutinib
Foonu alagbeka/Wechat/WhatsApp: +86-13681683526
Imeeli:lchen@syncozymes.com
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![Ibrutinib Intermediate 3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine](https://cdn.globalso.com/syncozymesnad/3-4-phenoxyphenyl-1H-pyrazolo34-dpyrimidin-4-amine.jpg)
Ibrutinib Intermediate 3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Àkójọ ìwé Nọ́mbà SZ-2028
CAS: 330786-24-8
Ìmọ́tótó: 99%
Lilo Ibrutinib
Foonu alagbeka/Wechat/WhatsApp: +86-13681683526
Imeeli:lchen@syncozymes.com
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Ibrutinib Intermediate 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile
Àkójọ ìwé Nọ́mbà SZ-2028-4
CAS: 330792-70-6
Ìmọ́tótó: 99%
Lilo 25kg/agba
Foonu alagbeka/Wechat/WhatsApp: +86-13681683526
Imeeli:lchen@syncozymes.com
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Phenylalanine dehydrogenase (PDH)
Nípa Phenylalanine dehydrogenase
ES-PDH: Ìsọ̀rí oxidoreductase kan. Ìhùwàpadà rere náà lè mú kí ìtúpalẹ̀ oxidative deamination ti iyọ̀ L phenylalanine ní iwájú NAD láti mú iyọ̀ phenylpyruvate jáde, àti pé ìhùwàpadà náà lè mú kí ìṣẹ̀dá iyọ̀ amino acid tí ó báramu láti inú iyọ̀ phenylpyruvate wáyé. Syncozymes ṣe àgbékalẹ̀ àwọn ohun 8 ti phenylalanine dehydrogenase (tí a kà sí ES-PDH-101~ES-PDH-108). A lè lo ES-PDH láti pèsè iyọ̀ phenylalanine tàbí iyọ̀ amino acid tí ó báramu láti inú iyọ̀ phenylpyruvic acid tàbí àwọn ohun tí ó yọrí sí.
Irú ìṣesí àbájáde:
Foonu alagbeka/Wechat/WhatsApp: +86-13681683526
Imeeli:lchen@syncozymes.com
