β-Nicotinamide Mononucleotide (NMN)
Laipe, awọn iroyin ti o dara wa ni aaye ti NMN - lẹhin atunyẹwo ti o muna nipasẹ igbimọ alamọdaju ti US Food and Drug Administration (FDA) agbari aṣẹ, awọn ohun elo NMN ti Shangke Biopharmaceutical (Shanghai) Co., Ltd. (lẹhinna tọka si si bi "Shangke Bio") ti ni ifọwọsi nipasẹ United States FDA NDI alakosile jerisi pe awọn oniwe-NMN aise awọn ohun elo le wa ni ifowosi lo ninu isejade, tita ati igbega ti ijẹun awọn afikun ni United States, ati ki o le wa ni ri lori awọn FDA osise. oju opo wẹẹbu bi afikun ohun elo aise ti ijẹẹmu tuntun, nọmba 1247.
FDA NDI jẹ eto ijẹrisi pataki julọ ni ọja AMẸRIKA.Gbigba iwe-ẹri yii kii ṣe tumọ si pe aabo ati didara awọn ọja Shangke Bio jẹmọ gaan, ṣugbọn tun jẹ itara si idagbasoke idiwọn igbagbogbo ti ile-iṣẹ NMN ni igba pipẹ.
| Orukọ Kemikali | β-Nicotinamide Mononucleotide |
| Awọn itumọ ọrọ sisọ | NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE 5'-PHOSPHATE |
| Nọmba CAS | 1094-61-7 |
| Òṣuwọn Molikula | 334.22 |
| Ilana molikula | C11H15N2O8P |
| EINECS: | 214-136-5 |
| Ojuami yo | 166°C(oṣu kejila) |
| iwọn otutu ipamọ. | -20°C |
| solubility | DMSO (Diẹ, Kikan), kẹmika (Diẹ), Omi (Diẹ) |
| fọọmu | ri to |
| awọ | Funfun to Yellow |
| Merck | 13.6697 |
| BRN | 3570187 |
| Iduroṣinṣin: | Hygroscopic pupọ |
| InChiKey | DAYLJWODMCOQEW-TURQNECASA-N |
| Nkan Idanwo | Awọn pato |
| Ifarahan | Funfun si pa-funfun kristali lulú |
| Iṣuu soda akoonu | ≤1% |
| pH iye (100mg/ml) | 2.0 ~ 4.0 |
| Mimo | ≥99.0% |
| Omi akoonu | ≤1% |
| Awọn irin ti o wuwo | <10ppm |
| Arsenic | <0.5ppm |
| Asiwaju | <0.5ppm |
| Makiuri | <0.1pm |
| Cadmium | <0.5ppm |
| Aloku olutayo | Ethanol≤1000ppm |
| Lapapọ Aerobic makirobia kika | <750cfu/g |
| Iwukara & Mold | <25cfu/g |
| Lapapọ coliform | ≤0.92MPN/g |
| E. Kọli | Odi |
| Salmonella | Odi |
| Staph.Aureus | Odi |
| Ayẹwo (lori ipilẹ anhydrous) | ≥99.0% |
| Sieving oṣuwọn | ≥95% |
| Olopobobo iwuwo | Iroyin fun alaye |
Apo:Igo, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Fipamọ ni wiwọ, awọn apoti sooro ina, fun ibi ipamọ gigun tọju ni 2 ~ 8 ° C tabi isalẹ.
Nicotinamide Mononucleotide (NMN) jẹ ẹya tuntun ti Vitamin B3 ti o jẹ iṣaju igbesẹ 1 si NAD + (Nicotinamide Adenine Dinucleotide).NMN jẹ olutọju NAD + cellular akọkọ lati jẹri pe o munadoko lati mu awọn sẹẹli pada ni vivo.
Nicotinamide Adenine Dinucleotide (NAD) jẹ ọkan ninu awọn ohun elo ti o ṣe pataki julọ ati ti o nifẹ ninu ara.O nilo fun diẹ ẹ sii ju awọn aati enzymatic 500 ati pe o ṣe awọn ipa pataki ninu ilana ti o fẹrẹ jẹ gbogbo awọn ilana ti ẹkọ pataki (Ansari ati Raghava, 2010).Ju gbogbo rẹ̀ lọ, ó lè jẹ́ kí a máa gbé ní ìlera àti ẹ̀mí gígùn.
Nicotinamide Adenine Dinucleotide (NAD) wa ni boya fọọmu oxidized rẹ (NAD+) tabi fọọmu ti o dinku (NADH), eyiti o jẹ awọn oludasiṣẹ pataki ti nọmba awọn oxidases.
SyncoZyems gẹgẹbi akọkọ lati gba ile-iṣẹ iṣelọpọ ohun elo aise ti FDA NDI NMN ti a fọwọsi, ṣe aṣoju aṣoju FDA gba NMN bi iru ohun elo tuntun le bẹrẹ lati gba ati fọwọsi fun awọn eroja afikun ijẹẹmu ni Amẹrika.
