β-Nicotinamide adenine dinucleotide fosifeti hydrate (NADP)
SyncoZymes (Shanghai) Co., Ltd jẹ olupilẹṣẹ asiwaju ati olupese ti β-Nicotinamide adenine dinucleotide phosphate hydrate (CAS: 53-59-8) pẹlu didara to gaju.A le pese COA, ifijiṣẹ agbaye, kekere ati titobi pupọ ti o wa.Ti o ba nifẹ si ọja yii, jọwọ firanṣẹ alaye alaye pẹlu nọmba CAS, orukọ ọja, opoiye si wa.Jọwọ kan si:lchen@syncozymes.com
| Orukọ Kemikali | β-Nicotinamide adenine dinucleotide fosifeti hydrate |
| Awọn itumọ ọrọ sisọ | β-Nicotinamide adenine dinucleotide fosifeti hydrate |
| Nọmba CAS | 53-59-8 |
| Òṣuwọn Molikula | 743.41 |
| Fọọmu Molecular | C21H28N7O17P3 |
| EINECS No. | 200-178-1 |
| iwọn otutu ipamọ. | Tọju ni aaye dudu, oju-aye aibikita, Itaja ni firisa, labẹ -20°C |
| solubility | H2O: 50 mg/ml, ko o, ofeefee die |
| pka | pKa1 3.9;pKa2 6.1 (ni 25℃) |
| o pọju | 260nm (tan.) |
| Merck | 14.6348 |
| Eto Iforukọsilẹ nkan EPA | Adenosine 5'- (trihydrogen diphosphate), 2'- (dihydrogen fosifeti), P'.fwdarw.5'-ester pẹlu 3- (aminocarbonyl) -1-.beta.-D-ribofuranosylpyridinium, iyọ inu (53-59- 8) |
| Nkan Idanwo | Awọn pato |
| Ifarahan | Funfun to ofeefee lulú |
| Solubility | 200mg / milimita ninu omi |
| pH iye (100mg/ml) | 5.0-7.0 |
| UV Spectral Analysis ni 260 nm ati pH 7.5 | (18± 1.0)×10³L/mol/cm |
| Akoonu (nipasẹ itupalẹ enzymatic pẹlu G6PDH ni pH 7.5, ni lilo spectrophotometer, abs.340nm, lori ipilẹ anhydrous) | ≥90.0% |
| Mimo (nipasẹ HPLC,%agbegbe) | ≥95.0% |
| Akoonu omi (nipasẹ KF) | ≤5% |
Apo:Igo, apo apamọwọ Aluminiomu, 25kg / Paali Drum, tabi gẹgẹbi ibeere alabara.
Ipò Ìpamọ́:Jeki ni wiwọ ni okunkun, fun ibi ipamọ gigun tọju ni 2 ~ 8℃.
NADP jẹ coenzyme kan, eyiti o jẹ nkan ninu eyiti nicotinamide adenine dinucleotide ati moleku fosifeti kan ni asopọ nipasẹ asopọ ester, ati pe o wa ni ibigbogbo.ni ti ibi aye.Awọn ohun-ini kemikali rẹ, spectrum gbigba, fọọmu redox, ati bẹbẹ lọ jẹ iru si NAD (Coenzyme I).NADP le jẹ lilo pupọ ni awọn aaticatalyzed nipasẹ ọpọlọpọ awọn dehydrogenases oti, ketoreductases ati awọn oxidoreductases miiran.Iru bii: o le dinku si NADPH nipasẹ ọpọlọpọ awọn dehydrogenases biibi 6-phosphoglucose dehydrogenase (EC.1.1.1.49), 6-phosphogluconate dehydrogenase (EC.1.1.1.44).Sibẹsibẹ, kii ṣe dandan ni anfani lati fesi pẹlu ọpọlọpọdehydrogenases ti o lo NAD, tabi ko le jẹ oxidized taara nipasẹ pq atẹgun.Ko dabi NAD, o wa ni pataki ni ipo idinku ninu awọn sẹẹli ti awọn oganisimu aerobic.
Gẹgẹbi lilo ọja, o le pin si awọn onipò wọnyi: ite biotransformation, ite reagent aisan, ite ounje ilera.
Ipele Biotransformation: O le ṣee lo fun iṣelọpọ ti awọn agbedemeji elegbogi ati awọn API, nipataki pẹlu awọn enzymu catalytic, gẹgẹ bi ketoreductase (KRED),P450 monooxygenase (CYP), formate dehydrogenase (FDH), glucose dehydrogenase (GDH), bbl Duro.
Iwọn reagent aisan: Pẹlu ọpọlọpọ awọn ensaemusi iwadii, bi ohun elo aise ti awọn ohun elo iwadii.
Iwọn ounjẹ ilera: Ohun elo afikun ijẹẹmu ti NADP jẹ pataki ninu iwadi ati ilana idagbasoke.
