Imine reductase (IRED)
Apejuwe kukuru:
Nipa Imine reductase
ES-IRED: Kilasi ti awọn enzymu ti o mu ki idinku C=N mnu si CN mnu.O jẹ ti enzymu redox, pẹlu coenzyme NADPH fun gbigbe hydrogen.Gẹgẹbi ayanfẹ chiral ti awọn ọja, wọn le pin si R-IRED ati S-IRED.Syncozymes ni idagbasoke 15 imine reductases (numbIRED ES-IRED-101-ES-IRED-115), eyiti o le ṣee lo ni lilo pupọ ni yiyan yiyan ati idinku stereoselective ti imines lati ṣeto awọn amines chiral.
Irisi ifasilẹ katalitiki:
Mobile/Wechat/WhatsApp: +86-13681683526
Imeeli:lchen@syncozymes.com
| Awọn enzymu | koodu ọja | Sipesifikesonu |
| Enzymu Powder | ES-IRED-101~ ES-IRED-114 | ṣeto ti 14 Imine Reductase, 50 mg kọọkan |
| 96-Daradara Enzyme waworan Apo | ES-IRED-1400 | ṣeto ti 14 Imine Reductase, 1 mg kọọkan |
★ Ga sobusitireti pato.
★ Alagbara chiral selectivity.
★ Ga iyipada.
★ Kere nipasẹ-ọja.
★ Ìwọnba lenu ipo.
★ Ore ayika.
Ni deede, eto ifaseyin yẹ ki o pẹlu sobusitireti, ojutu ifipamọ, henensiamu, coenzyme, ati eto isọdọtun coenzyme.
➢ Gbogbo iru awọn ES-IRED ti o baamu si ọpọlọpọ awọn ipo ifaseyin to dara julọ yẹ ki o ṣe iwadi ni ẹyọkan.
➢ Idojukọ giga tabi ọja pẹlu le ṣe idiwọ iṣẹ ES-IRED.Bibẹẹkọ, idinamọ le ni itunu nipasẹ afikun ipele ti sobusitireti.
Apẹẹrẹ 1 (Biosynthesis ti chiral 2-methyl pyrrolidine)(1):
Apeere 2(Biosynthesis of amine secondary)(2):
Apẹẹrẹ 3 (Idinku Awọn Imines Cyclic)(3):
Jeki 2 ọdun ni isalẹ -20 ℃.
Maṣe kan si pẹlu awọn ipo to gaju gẹgẹbi: iwọn otutu giga, giga / pH kekere ati idalẹnu Organic fojusi giga.
1. Scheller PN, Fademrecht S, Hofelzer S, et al.ChemBioChem, 2014, 15, 2201-2204.
2. Wetzl D, Gand M, Ross A, et al.ChemCatChem, 2016, 8, 2023-2026.
3. Li H, Luan ZJ, Zheng GW, et al.Adv.Synth.Catal.2015, 357, 1692-1696.
