Epoxide hydrolase (EH)
Apejuwe kukuru:
Nipa epoxide hydrolase
EH jẹ ether hydrolase ti o ṣe itọsi hydrolysis stereoselective ti awọn epoxides racemic lati ṣe agbejade 1, 2-diol ati awọn epoxides ti nṣiṣe lọwọ optically, eyiti o le ṣee lo fun ipinnu chiral ti epoxides tabi igbaradi ti awọn diol chiral.Wọn ti wa ni lilo pupọ ni oogun ati awọn aaye miiran.Awọn iru mẹta ti epoxide hydrolases awọn ọja (Nọmba bi ES-EH-101～ES-EH-103) ti dagbasoke nipasẹ SyncoZymes.ES-EH jẹ ohun elo ti o wulo lati ṣaṣepọ iṣelọpọ ti awọn ọti oyinbo chiral nipasẹ stereoselective hydrolysis ti aliphatic ati awọn epoxides aromatic.
Irisi ifasilẹ katalitiki:
Mobile/Wechat/WhatsApp: +86-13681683526
Imeeli:lchen@syncozymes.com
| Awọn enzymu | koodu ọja | Sipesifikesonu |
| Enzymu Powder | ES-EH-101 ~ ES-EH-103 | ṣeto ti 3 Epoxide Hydrolases, 50 miligiramu kọọkan 3 awọn ohun kan * 50mg / ohun kan, tabi awọn miiran opoiye |
| Apo iboju (SynKit) | ES-EH-300 | ṣeto ti 3 Epoxide Hydrolases, 1 mg kọọkan 3 awọn ohun kan * 1mg / ohun kan |
★ Ga sobusitireti pato.
★ Alagbara chiral selectivity.
★ Ga iyipada.
★ Kere nipasẹ-ọja.
★ Ìwọnba lenu ipo.
★ Ore ayika.
Ni deede, eto ifaseyin yẹ ki o pẹlu sobusitireti, ojutu ifipamọ (pH ifaseyin ti o dara julọ) ati ES-EH.
➢ Gbogbo iru awọn ES-EH ti o baamu si ọpọlọpọ awọn ipo ifaseyin to dara julọ yẹ ki o ṣe iwadi ni ẹyọkan.
➢ Idojukọ giga tabi ọja pẹlu le ṣe idiwọ iṣẹ ES-EH.Bibẹẹkọ, idinamọ le ni itunu nipasẹ afikun ipele ti sobusitireti.
Apẹẹrẹ 1(1):
Jeki 2 ọdun ni isalẹ -20 ℃.
Maṣe kan si pẹlu awọn ipo to gaju gẹgẹbi: iwọn otutu giga, giga / pH kekere ati idalẹnu Organic fojusi giga.
1. Kim YH, Lee I, Choi SH, ati Tal.J Mol Catal B-Enzym, 2013, 89: 48-51.
