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Nucloside phosphoryalse (NP)
Nipa nucleoside phosphoryalse
Awọn iru mẹta ti awọn ọja enzymu NP wa (Nọmba bi ES-NP-101 ~ ES-NP-103) ti a dagbasoke nipasẹ SyncoZymes.ES-NP-101 jẹ purine nucleoside phosphorylase, ES-NP-102 ati ES-NP-103 jẹ pyrimidine nucleoside phosphorylase.Nucleosidephosphorylase le decompose awọn nucleosides sinu awọn ipilẹ ati pentose fosifeti.Nucleoside phosphorylase ni a le pin si purine nucleoside phosphorylase ati pyrimidine nucleoside phosphorylase ni ibamu si ayanfẹ ti awọn ipilẹ nucleoside.Purine nucleoside phosphorylase le ṣe metabolize adenosine si adenine, inosine si hypoxanthine, guanosine si guanine, ati gbejade fosifeti ribose ni akoko kanna.Pyrimidine nucleoside phosphorylase le ṣe metabolize uridine si uracil ati gbejade fosifeti ribose.
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Hydroaminase (HAM)
Nipa Hydroaminase
Awọn oriṣi 2 ti ọja henensiamu HAM (Nọmba bi ES-HAM-101 ~ ES-HAM-102) ni idagbasoke nipasẹ SyncoZymes.HAM le mu amoniation ti enoic acid tabi awọn itọsẹ rẹ lati gbe awọn amino acids chiral jade.HAM le ṣee lo lati ṣepọ awọn amino acids chiral (tabi amines chiral) lati awọn enoic acids (tabi alkenes).Oluranlọwọ Amonia, gẹgẹbi omi amonia tabi iyọ ammonium, jẹ pataki.
Hydroaminase katalitiki lenu iru
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CALB aibikita
CALB
Recombinant Lipase B lati Candida antarctica (CALB) jẹ iṣelọpọ nipasẹ bakteria submerged pẹlu pichia pastoris ti a ṣe atunṣe nipa jiini.
CALB le ṣee lo ni ipele omi tabi Organic fase catalytic esterification, esterolysis, transesterification, oruka šiši polyester kolaginni, aminolysis, hydrolysis ti amides, acylation ti amines ati afikun lenu.
CALB jẹ pẹlu yiyan chiral giga ati yiyan ipo, nitorinaa o le ṣee lo ni lilo pupọ ni sisẹ epo, ounjẹ, oogun, ohun ikunra ati awọn ile-iṣẹ kemikali miiran.
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NADH oxidase (NOX)
Nipa NADH oxidase
ES-NOX (NADH oxidase): NOX ṣe itọsi oxidation ti NADH si NAD +, ati pe o jẹ ti oxidoreductase.Ninu ilana ti ifoyina, O2 jẹ pataki bi oxidant, ati dinku si H2O tabi H2O2.Awọn iru 4 wa ti awọn ọja enzymu NOX (ES-NOX-101 ~ ES-NOX-104) ti o dagbasoke nipasẹ ile-iṣẹ wa, eyiti o le ṣee lo fun isọdọtun oxidation ti coenzyme NAD +.
Iru ifaseyin katalitiki:
or
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Phenylalanine amonia lyase (PAL)
Nipa Phenylalanine amonia lyase
ES-PAL: Kilasi ti awọn ensaemusi ti o jẹ ki deamination taara ti L-phenylalanine si trans-cinnamic acid.Syncozymes ni idagbasoke awọn ohun 10 ti phenylalanine amonia lyase (ti a ṣe nọmba ES-PAL-101~ES-PAL-110), eyiti o le ṣee lo ni deamination tabi ifaseyin ti phenylalanine ati awọn itọsẹ rẹ.
Iru ifaseyin katalitiki:
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Catalase (CAT)
Nipa Catalase
ES-CAT (Catalase): ṣe itọsi jijẹjijẹ ti H2O2 sinu atẹgun ati omi.O wa ni akọkọ ni mitochondria, reticulum endoplasmic, ẹdọ ẹranko ati awọn sẹẹli ẹjẹ pupa, ni pataki ninu ẹdọ ni ifọkansi giga, pese iṣẹ aabo antioxidant fun ara.Ni biocatalysis, o jẹ lilo ni akọkọ lati yọkuro ifaseyin nipasẹ ọja-ọja hydrogen peroxide ati dinku idinamọ ati imuṣiṣẹ ti henensiamu nipasẹ hydrogen peroxide.Iru 1 nikan wa ti awọn ọja enzymu CAT ti o dagbasoke nipasẹ SyncoZymes (Nọmba bi ES-CAT).
Iru ifaseyin katalitiki:
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Lysine oxidase (LO)
Nipa Lysine oxidase
ES-LO (Lysine oxidase): ṣe itọsi ifoyina ti L-lysine si 6-amino-2-oxohexanoic acid (tabi lactone rẹ).Iru 1 kan ṣoṣo ti ọja henensiamu LO wa (Nọmba bi ES-LO) ti dagbasoke nipasẹ SyncoZymes.
Iru ifaseyin katalitiki:
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Phosphokinase (PKase)
Nipa Phosphokinase
ES-PKase (Phosphokinase): ṣe iyipada gbigbe ti awọn ẹgbẹ fosifeti lori ATP si awọn agbo ogun miiran.O tun ṣe itọsi gbigbe awọn ẹgbẹ fosifeti lori awọn nucleosides miiran ti triphosphate nigbakan.Pupọ awọn kinase nilo awọn ions irin divalent lati kopa ninu iṣesi (ni gbogbogbo Mg2+).Awọn iru 21 ti awọn ọja enzymu PKase wa (Nọmba bi ES-PKase101~ ES-PKase-121) ti dagbasoke nipasẹ SyncoZymes.
Irisi ifasilẹ katalitiki:
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Cyclooxygenase (COX)
Nipa Cyclooxygenase
ES-COX (Cyclooxygenase): n ṣe iyipada iyipada ti awọn iwe adehun C=C si epoxide.Awọn iru 11 wa ti awọn ọja enzymu COX (Nọmba bi ES-COX101 ~ ES-COX-111) ti a dagbasoke nipasẹ SyncoZymes.Gẹgẹbi ilana katalytic oriṣiriṣi, COX ti SyncoZymes ti pin si haloperoxidase ati styrene monooxygenase.ES-COX101, 102, 107-111 jẹ ti haloperoxidase, lakoko ti ES-COX103-106 jẹ ti styrene monooxygenase.
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Cyclohexanone monooxygenase (CHMO)
Nipa Cyclohexanone monooxygenase
ES-CHMO (Cyclohexanone monooxygenase): Baeyer Villiger monooxygenase (BVMO) kan pẹlu cyclohexanone gẹgẹbi sobusitireti, le oxidize cyclohexanone si cyclohexanol nipa lilo atẹgun.
O jẹ iru enzymu ti o gbẹkẹle flavin.Flavin oxidized ti dinku si flavin nipasẹ ọna ti idinku coenzyme II (NADPH) fun ifoyina atẹle.Nitorina, cofactor NADPH jẹ pataki ni flavin ọmọ.Iru 1 nikan wa ti ọja henensiamu CHMO (Nọmba bi ES-CHMO101) ti o dagbasoke nipasẹ SyncoZymes, eyiti o le ṣee lo lati oxidize cyclohexanone si cyclohexanone.
Iru ifaseyin katalitiki:
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Carboxylic acid reductase (CAR)
Nipa Carboxylic acid reductase
ES-CAR (Carboxylic acid reductase): ṣe itọsi idinku ti ẹgbẹ carboxyl si ẹgbẹ aldehyde.Ninu ilana katalitiki, imuṣiṣẹ ATP ati coenzyme NADPH nilo bi awọn gbigbe hydrogen.Awọn iru 2 ti awọn ọja enzymu CAR wa (Nọmba bi ES-CAR101 ~ ES-CAR-102) ni idagbasoke nipasẹ SyncoZymes.
Iru ifaseyin katalitiki:
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Transaldolase (TAL)
Nipa Transaldolase
ES-TAL (Transaldolase): nipataki n tọka si transaldolases threonine, eyiti o le ṣe itọsi esi lati ṣepọ awọn itọsẹ β-hydroxyphenylalanine pẹlu awọn itọsẹ threonine ati benzaldehyde.TAL jẹ enzymu ti o gbẹkẹle PLP.Iru 1 nikan wa ti ọja enzymu TAL (Nọmba bi ES-TAL101) ti o dagbasoke nipasẹ SyncoZymes, eyiti o le ṣee lo lati ṣajọpọ ti β-hydroxyphenylalanine ati awọn itọsẹ rẹ.
Iru ifaseyin katalitiki:
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